Pfizer Discontinues Axitinib Pancreatic Cancer Trial

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By: Tim Wright

Editor-in-Chief, Contract Pharma

Pfizer has discontinued a Phase III study of its investigational drug axitinib for the treatment of advanced pancreatic cancer. Based on an interim analysis, an independent Data Safety Monitoring Board (DSMB) found no evidence of improvement in the primary endpoint of survival in patients treated with axitinib and gemcitabine, compared to gemcitabine alone, the current standard of care for patients with advanced pancreatic cancer. “These results were disappointing, given the trend towards pro...

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